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ORIGINAL ARTICLE
CERVICAL AND OCULAR VESTIBULAR EVOKED MYOGENIC POTENTIALS IN MIGRAINE PATIENTS
1
Audio-Vestibular Unit, Department of Otolaryngology,, Kasr-Al-Ainy Faculty of Medicine, Cairo University, Egypt., Egypt
2
Neurology Department,, Kasr-Al-Ainy Faculty of Medicine, Cairo University, Egypt., Egypt
3
Audio-vestibular Unit, Department of Otolaryngology,, Suez-Canal University, Egypt, Egypt
A - Research concept and design; B - Collection and/or assembly of data; C - Data analysis and interpretation; D - Writing the article; E - Critical revision of the article; F - Final approval of article;
Publication date: 2021-08-31
Corresponding author
Abeir Osman Dabbous
Audio-Vestibular Unit, Department of Otolaryngology,, Kasr-Al-Ainy Faculty of Medicine, Cairo University, Egypt., Cairo University, 12211, Cairo, Egypt
Audio-Vestibular Unit, Department of Otolaryngology,, Kasr-Al-Ainy Faculty of Medicine, Cairo University, Egypt., Cairo University, 12211, Cairo, Egypt
J Hear Sci 2021;11(2):59-68
KEYWORDS
TOPICS
ABSTRACT
Background:
In migraine, there is no anatomical correlate of vertigo and no structural abnormality is evident in conventional imaging. Cervical vestibular-evoked myogenic potential (cVEMP) is an uncrossed inhibitory vestibulo-spinal reflex (VSR), while ocular VEMP (oVEMP) represents a crossed excitatory vestibulo-ocular reflex (VOR).
Objective:
This study aims at functional evaluation of the findings of cVEMP and oVEMP in migraine patients.
Material and methods:
This was a cross-sectional case-control study that included 20 migraine patients as the case group and 30 healthy adult subjects as a control group. All participants were subjected to history taking, otological examination, basic audiological evaluation, bedside examination of the dizzy patient, cVEMP, oVEMP, and posturography tests.
Results:
35% of migraine patients showed delayed cVEMP latency and 40% showed abnormal oVEMP in the form of statistically significant delayed right oVEMP P1 (p = 0.050) and left oVEMP N1 latency (p = 0.038) compared with controls. cVEMP parameters were not correlated to posturography results. The majority of migraine patients (70%) had normal equilibrium pattern and normal sensory analyses ratios (65%). Only 30% had vestibular dysfunction.
Conclusions:
VSR and VOR are affected in migraine patients. We recommend the use of cVEMP and oVEMP in migraine patients for functional assessment of brainstem pathways.
In migraine, there is no anatomical correlate of vertigo and no structural abnormality is evident in conventional imaging. Cervical vestibular-evoked myogenic potential (cVEMP) is an uncrossed inhibitory vestibulo-spinal reflex (VSR), while ocular VEMP (oVEMP) represents a crossed excitatory vestibulo-ocular reflex (VOR).
Objective:
This study aims at functional evaluation of the findings of cVEMP and oVEMP in migraine patients.
Material and methods:
This was a cross-sectional case-control study that included 20 migraine patients as the case group and 30 healthy adult subjects as a control group. All participants were subjected to history taking, otological examination, basic audiological evaluation, bedside examination of the dizzy patient, cVEMP, oVEMP, and posturography tests.
Results:
35% of migraine patients showed delayed cVEMP latency and 40% showed abnormal oVEMP in the form of statistically significant delayed right oVEMP P1 (p = 0.050) and left oVEMP N1 latency (p = 0.038) compared with controls. cVEMP parameters were not correlated to posturography results. The majority of migraine patients (70%) had normal equilibrium pattern and normal sensory analyses ratios (65%). Only 30% had vestibular dysfunction.
Conclusions:
VSR and VOR are affected in migraine patients. We recommend the use of cVEMP and oVEMP in migraine patients for functional assessment of brainstem pathways.
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