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REVIEW PAPER
NOVEL TRENDS IN THE MOLECULAR GENETICS OF HEARING
LOSS
1
Department of Genetics, World Hearing Center, Institute of Physiology and Pathology of Hearing,
Warsaw/Kajetany, Poland
Publication date: 2015-09-30
Corresponding author
Monika Oldak
Monika Oldak, Department of Genetics, World Hearing Center, Institute of Physiology and Pathology of Hearing, Mochnackiego Str. 10, 02-042 Warsaw, Mokra Str. 17, Kajetany, 05-830 Nadarzyn Poland, Tel.: +48-22-356-03-66; Fax: +48-22-356-03-67; e-mail: m.oldak@ifps.org.pl
Monika Oldak, Department of Genetics, World Hearing Center, Institute of Physiology and Pathology of Hearing, Mochnackiego Str. 10, 02-042 Warsaw, Mokra Str. 17, Kajetany, 05-830 Nadarzyn Poland, Tel.: +48-22-356-03-66; Fax: +48-22-356-03-67; e-mail: m.oldak@ifps.org.pl
J Hear Sci 2015;5(3):9-15
KEYWORDS
ABSTRACT
Genetically determined hearing loss is a highly heterogeneous disorder, and to date the analysis of its causes has been conducted selectively, covering only individual genes. Breakthroughs associated with current technological advances have contributed to a rapid development in the molecular genetics of hearing loss. Here we review a number of novel and important
achievements in the field: application of next-generation sequencing, novel genes, and trends in molecular therapies for hearing loss. Current achievements in the molecular genetics of hearing loss are discussed in the context of previously published
results and data from our own studies.
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