p-ISSN 2083-389x   e-ISSN 2084-3127

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RESULTS OF COCHLEAR IMPLANTATION IN CHILDREN WITH CONGENITAL CYTOMEGALOVIRUS INFECTION VERSUS GJB2 MUTATION

Raquel Ferreira, Jorge H. Martins, Marisa Alves, Jose Oliveira, Luis F. Silva, Carlos Ribeiro, António D. Paiva

(Department of Otorhinolaryngology, University and Hospital Center of Coimbra, Coimbra, Portugal)

JHS 2015; 5(2): OA36-41

DOI: 10.17430/892963

Published: 2015-08-31


BACKGROUND: Children with congenital cytomegalovirus (CMV) infection face a bigger risk of neurological deficits and developmental delays associated with sensorineural hearing loss (SNHL). Their rehabilitation with a cochlear implant (CI) may therefore be inferior to the paediatric population in general. This study describes post-implant outcomes in children with CMV-related deafness and compares them to children with genetic deafness caused by GJB2 mutation (connexin 26) rehabilitated at the Centro Hospitalar e Universitário de Coimbra, Portugal.
MATERIAL AND METHODS: We conducted a revision of 11 children with profound hearing loss caused by congenital CMV infection rehabilitated with a CI in our institution. The children were divided into 3 groups according to age of implantation (<2 years, 2–3 years, >3 years) and their performance was compared to a group of children with genetic hearing loss caused by GJB2 mutation. To compare performance the following tests were applied: SIR, CAP, vocal characteristics evaluation grid (VCEG), MAIS, and MUSS.
RESULTS: We found no differences between the two groups in terms of hearing thresholds obtained with a CI. In spite of a wider spread of results in the CMV group, there were no significant statistical differences in the SIR and VCEG tests or in the MAIS and MUSS questionnaires. There was a significant difference in the CAP test (p=0.049) where the GJB2 group had superior results.
CONCLUSIONS: The present study has shown that the CMV group had poorer results for the CAP test and a wider spread of results in the other tests. However, the CMV group attained results comparable to children with profound hearing loss and no other deficit, and benefited from rehabilitation with a cochlear implant.

Keywords: Cochlear Implants, Cytomegalovirus Infections, Deafness



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