Current Issue
Volumes and Issues
For Authors
Manuscript Guidelines
Review Process
Conflict of Interest
Copyright
About the Journal
Editorial Board
Aim and Scope
Policy and Ethical Guidelines
Promotion of the Journal
Print-Version Subscription
Publisher and Contact Information
Contact Information
Sign in
ORIGINAL ARTICLE
TEST OF MODIFIED ULTRA-HIGH MOLECULAR WEIGHT
POLYETHYLENE FOR PROSTHETIC REPAIR OF THE
OSSICULAR CHAIN
1
Department of Otorhinolaryngology, Grodno State Medical University, Belarus
2
Faculty of Innovative Technologies of Mechanical Engineering, Grodno State University, Belarus
Publication date: 2013-03-31
Corresponding author
Uladzimir Novasialetski
Novasialetski Uladzimir, 80 ul. Gorkogo, Grodno 230009, Belarus, Phone: +375-152-43-54-51, e-mail: novasialetski@rambler.ru
Novasialetski Uladzimir, 80 ul. Gorkogo, Grodno 230009, Belarus, Phone: +375-152-43-54-51, e-mail: novasialetski@rambler.ru
J Hear Sci 2013;3(1):27-34
KEYWORDS
ABSTRACT
Background:
Our aim was to evaluate the effect of implantation of a surface-modified ultra-high molecular weight polyethylene (UHMWPE) of high density into a rabbit ear’s bulla in terms of biochemical and immunological blood parameters and middle ear tissue morphology.
Material and Methods:
Exactly 35 rabbits were used, divided into 3 groups. In the 1st group the ears were implanted with a piece of UHMWPE 6 mm long and 1 mm in diameter the surface of which had been modified with a laser. In the 2nd group similar titanium implants were used. The 3rd group was a control (5 rabbits). The 1st and 2nd groups comprised 15 animals which were euthanased 15, 60, and 90 days after implantation (5 animals each).
Results:
Comparison of the two experimental groups with the control group revealed no significant differences in biochemical and immunological blood parameters or tissue morphology in the middle ear at different times after surgery
Conclusions:
UHMWPE of high density can be regarded as a material suitable for developing prostheses for the ossicular chain.
Our aim was to evaluate the effect of implantation of a surface-modified ultra-high molecular weight polyethylene (UHMWPE) of high density into a rabbit ear’s bulla in terms of biochemical and immunological blood parameters and middle ear tissue morphology.
Material and Methods:
Exactly 35 rabbits were used, divided into 3 groups. In the 1st group the ears were implanted with a piece of UHMWPE 6 mm long and 1 mm in diameter the surface of which had been modified with a laser. In the 2nd group similar titanium implants were used. The 3rd group was a control (5 rabbits). The 1st and 2nd groups comprised 15 animals which were euthanased 15, 60, and 90 days after implantation (5 animals each).
Results:
Comparison of the two experimental groups with the control group revealed no significant differences in biochemical and immunological blood parameters or tissue morphology in the middle ear at different times after surgery
Conclusions:
UHMWPE of high density can be regarded as a material suitable for developing prostheses for the ossicular chain.
REFERENCES (21)
1.
Pluzhnikov MS, Diskalenko VV, Kurmashova LM. The current state of a problem of surgical rehabilitation of patients with chronic inflammatory diseases of a middle ear. Vestnik otorinolaringologii, 2006; 5: 31–34.
2.
Weerda H. History of auricular reconstruction. Adv Otorhinolaryngol, 2010; 68: 1–24.
3.
Sitnikov VP, Anikin IA, Chernushevich AI, Zavarzin BA, Anikin MI. Use of autografts and implants at ossiculoplasty. Vestnik otorinolaringologii, 2006; 2: 38–41.
4.
Khorov OG, Melanyin VD. Surgical treatment of patients by the destructive inflammation of middle ear. Grodno: GrSMU, 2001.
5.
Chernushevich AI, Aleksandrov IN. The comparative characteristic of the prosthesises used at ossiculoplasty. Russian Otorhinolaryngology, 2004; 1: 113–15.
6.
Semenov FV, Volik AK. Clinical and audiological methods of an assessment of effectiveness ossiculoplasty with use of titanic prosthesises at surgical treatment of patients by chronic inflammation of middle ear. Russian Otorhinolaryngology, 2004; 4: 145–48.
7.
Luers JC, Huttenbrink KB, Beutner D. Incus to stapes footplate reconstruction of the ossicular chain using titanium implants. Clin Otolaryngol, 2010; 35(2): 161–62.
8.
Ceccato SB, Maunsell R, Morata GC, Portmann D. Revue Comparative results of type II ossiculoplasty: incus transposition versus titanium PORP (Kurz). Rev Laryngol Otol Rhinol, 2005; 126(3): 175–79.
9.
Dalchow CV, Grün D, Stupp HF. Reconstruction of the ossicular chain with titanium implants. Otolaryngology-Head and Neck Surgery, 2001; 125(6): 628–30.
10.
Vasilenko SP, Nikolaev MT, Nikolaev PM. Polymeric and ceramic-metal materials in reconstructive and plastic surgery of posttraumatic craniofacial damages. Russian Otorhinolaryngology, 2003; 4: 86–90.
11.
Pinchuk of HP, Nikolaev VI, Tsvetkova EA. Prosthetic repair of joints: technical and medical-biological aspects. Gomel: IMMS NASB, 2003.
12.
Dong, HY, Joon HN. Readjustable Sling Procedure for the Treatment of Female Stress Urinary Incontinence with Intrinsic Sphincter Deficiency: Preliminary Report. Korean J Urol, 2010; 51(6): 420–25.
13.
Struk VA. Materials science. Minsk: Data-processing center of the Ministry of Finance; 2008.
14.
Avdeychik SV. Nanocomposition machine-building materials: experience of development and application. Grodno: GrSU, 2006.
15.
Andreev IN. Ultra-high molecular weight polyethylene of high density. Leningrad: Chemistry, 1982.
16.
Razdorsky VV. Nickelid titanium implants biocompatibility evaluation in animal. Odontology, 2008; 6: 9–12.
17.
Sorokin VG, Eysymont EI. Influence of a laser radiation on structural parameters of polymeric materials. Vestnik of GrSU, 2009; 2(82): 109–16.
18.
Sapoznicov AG, Dorosevich AE. Histologic and microscopic technique: management. Smolensk: SAU, 2000.
19.
Kamyshnikov VS. Directory on clinical-biochemical laboratory diagnostics. Part 1. Minsk: Belarus, 2002.
20.
Kamyshnikov VS. Directory on clinical-biochemical laboratory diagnostics. Part 2. Minsk: Belarus, 2002.
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
